HLA Laboratory

College of American Pathologists (CAP), and the United Network for Organ Sharing (UNOS), ClinImmune Labs and its accredited technical staff are committed to providing the highest quality histocompatibility testing services for research studies as well as clinical transplantation and transfusion programs in Colorado, across the U.S. and abroad.

Testing available for:

  • Immunotherapy
  • Clinical Transplantation- solid organ and hematopoietic stem cell
  • Platelet Transfusion support
  • Genetic HLA Disease Association
  • Post-Transplant DSA risk and monitoring

Clinically Approved Assays:

  • HLA-A, B, C, DRB1/3/4/5, DQA1, DQB1, DPA1, DPB1 loci
    • Low to high resolution testing
  • HLA Antibody Detection
    • Panel Reactive Antibody, including HLA Specificity Analysis
    • Titration/Quantitation studies for pre-transplant immunotherapy protocols
    • Crossmatching for transplant compatibility
    • Platelet support panels to assess allo-reactive HLA antibodies and HLA-A,B typing for selection of matched platelets
  • KIR genotyping

Services Provided:

  • Initial consultations provided for test selection, cost effectiveness, sample and turn-around time requirements
  • Immunogenetics testing (e.g. HLA-B*57:01 screening test to determine susceptibility to abacavir hypersensitivity syndrome and HLA-B27 which may assist in the diagnosis of ankylosing spondylitis, juvenile rheumatoid arthritis, and Reiter’s syndrome)
  • Transplant Immunology Teleconferences presented at ClinImmune
  • Customized requisitions and clear, concise reports; electronic data transfer
  • Additional test interpretation consults upon request
  • Donor search strategy support
  • Analysis of HLA allele frequency

HLA epitope analysis


What We Do

Accreditations Certificates

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We have provided FDA-Approved stem-cell therapies to over 2,000 patients